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DeCS
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Descriptor English:
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Nogo Proteins
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Descriptor Spanish:
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Proteínas Nogo
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Descriptor Portuguese:
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Proteínas Nogo
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Synonyms English:
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NI 220 Protein
NI 250 Protein
NI 35 250
NI 35 Protein
NI-220 Protein
NI-250 Protein
NI-35 Protein
NI-35-250
Neurite Growth Inhibitor 35 350
Neurite Growth Inhibitor 35-350
Nogo 66 Protein
Nogo A Protein
Nogo B Protein
Nogo C Protein
Nogo Protein
Nogo-66 Protein
Nogo-A Protein
Nogo-B Protein
Nogo-C Protein
Reticulon 4 B Protein
Reticulon 4 Protein
Reticulon 4-B Protein
Reticulon-4 Protein
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Tree Number:
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D12.776.543.620.738
D12.776.631.580.738
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Definition English:
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Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system. |
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History Note English:
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2017 (2000)
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Allowable Qualifiers English:
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Record Number:
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56639
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Unique Identifier:
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D000070798
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Occurrence in VHL:
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Similar:
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DeCS
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